Pain and Why it Becomes Chronic? (Lecture 1)
In 2021 about 56 million US adults experienced chronic pains. 17 million experienced high-impact chronic pains. Pandemic has contributed to a significant new cases. We are starting a series to understand what pain is, the anatomy, physiology, pathology, and the management aspects will be covered in this mini-series on pain. Let's start with pain, pain transduction, pain pathways, and pain modulation in this talk.
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#drbeen #koolbeens #PAIN
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References
DrBeen.Com
Chronic Pain Among Adults — United States, 2019–2021 | MMWR
https://www.cdc.gov/mmwr/volumes/72/wr/mm7215a1.htm
The Revised IASP definition of pain: concepts, challenges, and compromises - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680716/
Untitled Document
https://www.rnceus.com/ages/nociceptive.htm
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/
Physiology, Enkephalin - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK557764/
Pain Modulation - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/pain-modulation
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/
Pain Tracts and Sources (Section 2, Chapter 7) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston
https://nba.uth.tmc.edu/neuroscience/m/s2/chapter07.html
Therapeutic Basis of Clinical Pain Modulation - Kirkpatrick - 2015 - Clinical and Translational Science - Wiley Online Library
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12282
Pain Tracts and Sources (Section 2, Chapter 7) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston
https://nba.uth.tmc.edu/neuroscience/m/s2/chapter07.html
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/#:~:text=The%20pathway%20for%20pain%20transmission,is%20derived%20from%20animal%20studies.
Pain Modulation - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/pain-modulation
Untitled Document
https://www.rnceus.com/ages/nociceptive.htm
Physiology, Enkephalin - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK557764/
Moving Beyond Pain as the Fifth Vital Sign and Patient Satisfaction Scores to Improve Pain Care in the 21st Century - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878703/
,,-gsLxPagNB8,UCrtd2wePvAl6RN_D-9jWVQQ, Health,Knowledge, channel_UCrtd2wePvAl6RN_D-9jWVQQ, video_-gsLxPagNB8,What Are Reactive Oxygen Species and Lipid Species?
Let's understand the foundational components of inflammation reactive oxygen and reactive lipid species.
If you like this content and want more, I am doing a special membership offer. Click here:
https://www.drbeen.com/
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Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
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PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/
#drbeen #koolbeens #diabetes
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,,hRCac7xcAtg,UCrtd2wePvAl6RN_D-9jWVQQ, Health, channel_UCrtd2wePvAl6RN_D-9jWVQQ, video_hRCac7xcAtg,Erratum: Quercetin is primarily lipid soluble and weakly water soluble. I have put it in an incorrect category.
Which Antioxidants To Use Together?
As we use antioxidants for aches and pains/inflammation we need to keep in mind the water or lipid solubility of the molecule. Let's review.
If you like this content and want more, I am doing a special membership offer. Click here:
https://www.drbeen.com/
Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true
PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/
#drbeen #koolbeens #diabetes
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
,1,Simple Plan to Control Inflammation
Here is an important list of anti-inflammatory molecules to help manage inflammation.
Want to get access to DrBeen at low price of $4.99/month? Click here: https://www.drbeen.com/med-nerd/
Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
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PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/
#drbeen #Inflammation #Supplements
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References:
Visit articles related to these topics and see the references at the end: https://www.drbeen.com/articles/category/chronic-inflammation/
,1,Vitamin D May Reduce Fiery Death of Cells and Resulting Severe Inflammation
Vitamin D receptor activation leads to reduced pyroptosis, and a shift towards autophagy and apoptosis. Let's review the mechanism of pyroptosis and the studies about vitamin D's role in preventing pyroptosis.
Want to get access to DrBeen at low price of $4.99/month? Click here: https://www.drbeen.com/med-nerd/
Want to support this work?:
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#drbeen #Inflammation #VitaminD
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Friday, Jun. 21 2024 16:18 PM
Autophagy, Pyroptosis, and Ferroptosis: New Regulatory Mechanisms for Atherosclerosis - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793783/
Vitamin D/VDR attenuate cisplatin-induced AKI by down-regulating NLRP3/Caspase-1/GSDMD pyroptosis pathway - ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S0960076020303149
Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904361/
Pyroptosis: mechanisms and diseases | Signal Transduction and Targeted Therapy
https://www.nature.com/articles/s41392-021-00507-5
Effects of Vitamin D3 Supplementation and Aerobic Training on Autophagy Signaling Proteins in a Rat Model Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10535215/
Apoptosis Induced by Vitamin D Compounds in Breast Cancer Cells Is Inhibited by Bcl-2 but Does Not Involve Known Caspases or p531 | Cancer Research | American Association for Cancer Research
https://aacrjournals.org/cancerres/article/59/19/4848/505530/Apoptosis-Induced-by-Vitamin-D-Compounds-in-Breast
Morphological Features of Organelles during Apoptosis: An Overview - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972681/
,1,Omega-3 Reduces Chronic Inflammation and Neurosurgical Pain
Two studies demonstrating the power of omega-3 to reduce inflammation and neurosurgical pain.
Want to get access to DrBeen at low price of $4.99/month? Click here: https://www.drbeen.com/med-nerd/
Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true
PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/
#drbeen #koolbeens #Health #omega3
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Reference:
Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain - PubMed https://pubmed.ncbi.nlm.nih.gov/16531187/
An Oily Fish Diet Improves Subclinical Inflammation in People at High Cardiovascular Risk: A Randomized Controlled Study - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199776/
Study Details | Effects of Dietary Polyphenols and ω-3 Fatty Acids on Cardiovascular Risk Factors in High Risk Subjects | ClinicalTrials.gov https://clinicaltrials.gov/study/NCT01154478
Table - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8199776/table/molecules-26-03369-t001/
University of Naples Federico II - Wikipedia https://en.wikipedia.org/wiki/University_of_Naples_Federico_II
,1,Pain and Why it Becomes Chronic? (Lecture 1)
In 2021 about 56 million US adults experienced chronic pains. 17 million experienced high-impact chronic pains. Pandemic has contributed to a significant new cases. We are starting a series to understand what pain is, the anatomy, physiology, pathology, and the management aspects will be covered in this mini-series on pain. Let's start with pain, pain transduction, pain pathways, and pain modulation in this talk.
If you like this content and want more, I am doing a special lifetime membership offer. Click here:
https://www.drbeen.com/yt-special-p/
Want to support this work?:
Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed
Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true
PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/
#drbeen #koolbeens #PAIN
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References
DrBeen.Com
Chronic Pain Among Adults — United States, 2019–2021 | MMWR
https://www.cdc.gov/mmwr/volumes/72/wr/mm7215a1.htm
The Revised IASP definition of pain: concepts, challenges, and compromises - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680716/
Untitled Document
https://www.rnceus.com/ages/nociceptive.htm
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/
Physiology, Enkephalin - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK557764/
Pain Modulation - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/pain-modulation
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/
Pain Tracts and Sources (Section 2, Chapter 7) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston
https://nba.uth.tmc.edu/neuroscience/m/s2/chapter07.html
Therapeutic Basis of Clinical Pain Modulation - Kirkpatrick - 2015 - Clinical and Translational Science - Wiley Online Library
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12282
Pain Tracts and Sources (Section 2, Chapter 7) Neuroscience Online: An Electronic Textbook for the Neurosciences | Department of Neurobiology and Anatomy - The University of Texas Medical School at Houston
https://nba.uth.tmc.edu/neuroscience/m/s2/chapter07.html
The Anatomy and Physiology of Pain - Pain and Disability - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK219252/#:~:text=The%20pathway%20for%20pain%20transmission,is%20derived%20from%20animal%20studies.
Pain Modulation - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/pain-modulation
Untitled Document
https://www.rnceus.com/ages/nociceptive.htm
Physiology, Enkephalin - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK557764/
Moving Beyond Pain as the Fifth Vital Sign and Patient Satisfaction Scores to Improve Pain Care in the 21st Century - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878703/